Knowledge Foudnation Conference: Single-Molecule Analyses and the Emergence of Applications

Single-Molecule Analyses and the Emergence of Applications

August 19-20, 1999 ~ Omni Parker House ~ Boston, MA USA

[ Background | Program Features | Agenda | Participants | Register ]

Exciting advances in single-molecule detection turned researcher's attention toward new analytical approaches in efforts to move technology in the direction of "real world" applications.

This conference will focus not only on advances in detection, but also improvements in low light imaging devices, thin film filters and manipulation using optical tweezers and laser microbeams. Analyses of single-molecule mechanisms and biomolecular functions through observation of real time turnovers, adsorption at solid/liquid interfaces and other cutting edge methods will be discussed in depth.

Leading researchers from academia, industry and government labs will address techniques such as fluorescence and scanning probe as well as problematic nanoenvironments and measurements. Efforts to improve materials, further high sample throughput, and build micro devices are on the verge of realization.

Will observing and manipulating some of the smallest building blocks of biological and synthetic materials lead to new applications and technologies? Increase your understanding of how single molecule research can benefit biotechnology, biomedicine, forensics, materials science, molecular electronics and molecular machines.

Be a part of this timely and one of kind meeting -- Register Today!

Program Features:

Biomolecular and Material Approaches

  • Enzymatic Dynamics
  • "On the fly" Detection and Extended Observation Techniques
  • Nanoscale Environments in Silicate and Polymer Films
  • Adsorption to Polish Fused Silica

Instrumentation and Techniques

  • Probing Single-Molecule Interactions and Reactions
  • True 3-D Orientational Probes
  • Ultrasensitive Detection of Specific Nucleic Acid Sequences
  • Two-Photon High Resolution Near-Field Microscopy

Biomolecular Sensors and Biomolecular Machines

  • Emerging Biomedical Applications
  • Fabrication of Micro-devices for Genomics and Near-IR Fluorescence
  • Quantitative Molecule by Molecule RNA
  • Technical Solutions for Analyte Concentration and High Sample Throughput
  • Recent Advances with Nanoparticles
  • Hybrid living/Nonliving Systems for Devices (NEMs)
  • Single Molecular Electronics and Chemistry at the Atomic Scale
  • Quantum Molecular Dynamics Simulations
CONFERENCE AGENDA
Thursday, August 19, 1999

7:00   Registration: Coffee, Danish

8:00 Chairperson's Opening Remarks
Norman J. Dovichi

BIOMOLECULAR SESSION

8:15   Single-Molecule Enzymology
Norman J. Dovichi

8:50   Single-Molecule Enzymatic Dynamics
X. Sunney Xie

9:25   Refreshment Break/Poster Viewing

9:45   Single-Molecule Biochemistry in the Light Microscope: Facts and Perspectives
Karl Otto Greulich

10:20   Manipulating the Nanoenvironment around Single Molecules with Vesicles
Daniel T. Chiu, Department of Chemistry, Harvard University

MATERIALS, SURFACES AND INTERFACES SESSION

10:55   Isolation, Manipulation, and Imaging of Single Molecules in Polymer Micro- and Nanoparticles
Michael D. Barnes

11:30   Luncheon



1:00   Nanoscale Environments in Silicate and Polymer Films Characterized by Single Molecule Spectroscopy
Daniel A. Higgins

1:35   Single-Molecule Probing of Strong Adsorption of Small Molecules and of Proteins at Solid/Liquid Interfaces
Mary J. Wirth

INSTRUMENTATION AND ANALYTICAL TECHNIQUES SESSION

2:10   Advances in Low Light Imaging Devices for Single Molecule Fluorescence
Mark Christenson

2:45   Probing Single Molecule Interactions and Reactions
Weihong Tan

3:20   Refreshment Break/Poster Viewing

3:40   Single Molecule Orientation Probes
Robert M. Dickson

4:15   Ultrasensitive Detection of Specific Nucleic Sequences
Alonso Castro

4:50   Optical Thin Film Filters - Developments to Enable Single Molecule Analyses and Applications Technology
Steven E. Morin

5:25   Two-Photon High Resolution Near-Field Microscopy Fluorescence Imaging with a Metal Tip
Erik Sanchez

6:00   Cocktail Reception/Cash Bar

Friday, August 20, 1999

8:00   Coffee & Danish

8:30   Chairperson's Remarks
Paul S. Weiss

BIOMOLECULAR SENSORS AND BIOMOLECULAR MACHINERY SESSION

8:35   Emerging Applications of Single-Molecule Analysis in Biomedical Sciences
X. Nancy Xu

9:10   Single Molecule Analysis in Genomics using Micro-Devices and Near-Infrared Fluorescence: A Logical Choice
Steven A. Soper

9:45   Refreshment Break/Poster Viewing

10:05   Dendritic Single Molecule Detection
Thor W. Nilsen

10:40   Counting Single Molecule at Interfaces
Stefan Seeger

11:15   Optically Active Nanoparticles for Single-Molecule Detection and Spectroscopy
Shuming Nie



12:00   Lunch on Your Own

1:30   Integrating Life Processes into Engineered Nanofabricated Systems
Carlo D. Montemagno

2:05   Probing Single Molecular Electronics and Chemistry at the Atomic Scale Using Scanning Tunneling Microscopy and Spectroscopy
Paul S. Weiss

2:40   Molecular Machines and Electronics: Simulations
Deepak Srivastava

3:15   Closing Remarks
Michael Becker, Senior Research Manager, Gen-Probe

3:30   End of Conference

PARTICIPATING ORGANIZATIONS

Cornell University

Genisphere Inc.

Gen-Probe

Georgia Institute of Technology

Harvard University

Indiana University

Institut fur Molekulare Biotechnologie

Kansas State University

Los Alamos National Laboratory

Louisiana State University

NASA Ames Research Center

Oak Ridge National Laboratory

Old Dominion University

Omega Optical, Inc.

Roper Scientific (RS-Photometrics, RS-Princeton Instruments)

The Pennsylvania State University

University of Alberta

University of Delaware

University of Florida

Universitate Regensburg

Unable to Attend?
You can purchase a full set of conference documentation. Simply check the box on the conference documentation order form and mail us your payment of US$395. Please allow 4 weeks after the conference date for delivery.
Registration Information

 Registration fee includes lunch on the first day, reception, refreshments and all documentation made available to us by speakers. Commercial registration is US$1295. An academic rate of US$895 is extended to all participants registering as full time employees of government and universities. To recieve the academic/government rate you must not be affiliated with any private organizations either as consultants or owners or part owners of businesses. On-site registration is an additional $100.

Payment: All payments must be made in U.S. funds drawn on a U.S. bank. Please make check(s) payable to The Knowledge Foundation, Inc. and attach to the registration form even if you have registered by phone, fax or e-mail. Payment is required prior to the conference to confirm your registration. Confirmation of your booking will follow.

Discount Accommodations and Travel: A block of rooms has been allocated at a special reduced rate. Please make your reservations directly by July 19, 1999. When making reservations, please refer to the The Knowledge Foundation. Contact The Knowledge Foundation if you require assistance.

Venue:
Omni Parker House
60 School Street
Boston, MA 02108
Tel: (617) 227-8600
Fax: (617) 742-5729

The Knowledge Foundation's official travel agent, Aries Travel can assist you in making all your air travel arrangements. For more information contact Aries Travel at 617-720-1420.

Substitutions/Cancellations: A substitute member of your company may replace your attendance at any time at no charge if you find your schedule prevents you from attending. Please notify us immediately so that materials can be prepared. If you do not wish to substitute your registration, we regret that your cancellation will be subject to a $100 processing fee. To receive a prompt refund, we must receive your cancellation in writing 15 days prior to the conference. Unfortunately cancellations cannot be accepted after that date. In the event that The Knowledge Foundation, Inc. cancels an event, The Knowledge Foundation, Inc. cannot resume responsibility for any travel-related costs.

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