Knowledge Foundation Conference: Using Combinatorial Approaches for New Materials Discovery -- Polymers, Catalysis, Electronic Materials -- January 21-22, 1999 -- San Jose, California

Designed Specifically for Organizations Exploring One of the Most Exciting Scientific Debates Today.....

How does the combinatorial approach compare with other scale-up technologies for lead identification AND optimization?

[ Background | Agenda | Participants | Survey/Posters | Registration Info ]


Combinatorial approaches have been highly successful in pharmaceutical applications and are just emerging within the materials industries. Though the approach has, for the most part, been applied to industrially interesting materials only within the last few years, already, scientific papers indicate impressive results and successful utilization of the approach.

However, while the potential -- hundreds of thousands of experiments per day -- is quite tantalizing, many questions remain as to how to usefully apply this approach within the context of industry's requirements and pressures.

National efforts are being proposed to help reduce the costs of entry for many industries by establishing programs to help overcome the technological hurdles that remain as well as to help spur collaborative partnerships among government, academia and industry.

In the U.S., Dr. John Hewes, who is speaking at this conference, is currently working on a proposal to establish an NIST/ATP program to spur investment in this technology. In Japan, Professor Hideomi Koinuma, another speaker at this conference is spearheading a national effort to apply combi-chemistry to all areas of materials.


CONFERENCE AGENDA

Thursday, January 21, 1999
PLENARY SESSION

8:00   Registration, Poster Set-Up, Coffee & Danish

9:00   Welcome & Introduction

9:05   Chairperson's Remarks
John D. Hewes

9:10   Combinatorial Discovery of Chemicals and Materials: A NIST/ATP Project Portfolio
John D. Hewes

9:25   Applications of Combinatorial Chemistry to Drug Discovery
Joseph C. Hogan, Jr.

10:00   Combinatorial Methodologies for Materials Discovery and Optimization
Henry Weinberg

10:35   Poster Viewing & Refreshment Break

11:00   Effective Utilization of High Throughput Screening (HTS) and Related Technologies
Marianne Asaro

11:35   High Throughput Experimentation: Computation Requirements
John M. Newsam

12:10   Panel Discussion: Choosing Appropriate Targets of Opportunity
Moderator

John D. Hewes

12:30   Luncheon

Three concurrent Breakout Sessions will follow the luncheon -- see below


Thursday, January 21, 1999
CONCURRENT BREAKOUT SESSION I: POLYMERS

Chairperson: Joachim Kohn

2:00   Role of Combinatorial Chemistry in Polymerization Catalyst Development
Michael E. Muhle

2:35   The Use of A-B Copolymers in the Design of Combinatorial Polymer Libraries
Joachim Kohn

3:10   Libraries of Supramolecular Dendrimers
Virgil Percec

3:45   Poster Viewing & Refreshment Break

4:15   Combinatorial Strategies for Characterizing Polymeric Materials
Damian A. Hajduk

4:50   Design and Development of a Combinatorial Chemistry Reaction Block Specifically for the Materials Sciences Industry
Rudy Haidle

5:30   Reception & Cash Bar


Thursday, January 21, 1999
CONCURRENT BREAKOUT SESSION II: ELECTRONIC MATERIALS

Chairperson: Randolph E. Treece

2:00   Combinatorial Microlab Investigation of Copper-Corrosion Mechanisms
Michael E. Muhle

2:35   Synchrotron X-Ray Microbeam Diagnostics of Combinatorial Synthesis
Eric D. Isaacs

3:10   Combinatorial Search and Optimization of Phosphors and Scintillators*
Ted X. Sun

3:45   Poster Viewing & Refreshment Break

4:15   Approaches to Improved Transparent Conducting Oxides and Large-Scale Characterization of Film Libraries
Randolph E. Treece

4:30   Searching for Thin-Film Dielectrics using a Compositional-Spread Approach
Lynn F. Schneemeyer

5:05   Combinatorial Ion Implantation and Ion Beam Analysis of Silicon-Based Luminescent Material Chip
Min-Qian Li

5:30   Reception & Cash Bar


Thursday, January 21, 1999
CONCURRENT BREAKOUT SESSION III: CATALYSIS

Chairperson: Selim Senkan

2:00   Combinatorial Computational Chemistry Approaches to the Design of Heterogeneous Catalysts
Akira Miyamoto

2:35   Automated Combinatorial Hydrothermal Synthesis of Molecular Sieves
Thomas Bein

3:10   High Throughput Screening of Catalyst Libraries
Selim Senkan

3:45   Poster Viewing & Refreshment Break

4:15   Combinatorial Approaches to Heterogeneous Catalysis
Peter J. Desrosiers

4:30   Combinatorial Approaches to Olefin Polymerization Catalysis
Vincent Murphy

5:30   Reception & Cash Bar


Friday, January 22, 1999
PLENARY SESSION

8:30   Poster Viewing & Coffee

9:00   Chairperson's Remarks
Marianne Asaro

9:05   Application of Combinatorial Synthesis to New Laser Materials
Richard Schlecht

9:40   Combinatorial Epitaxy for Exploration of Electrofunctional Materials and Junctions
Hideomi Koinuma

9:25   Applications of Combinatorial Chemistry to Drug Discovery
Joseph C. Hogan, Jr.

10:15   Poster Viewing & Refreshment Break

10:30   Combinatorial Synthesis and High Throughput Evaluation of Functional Solid State Materials
X-D. Xiang

11:05   The Role of Combinatorial Chemistry in Identifying Stable, Volatile Compounds
William S. Rees, Jr.

11:35   High Throughput Experimentation: Computation Requirements
John M. Newsam

11:40   Panel Discussion: Synergistic Technologies and Comparative Review
Moderators: J. Charles Barbour and Michael Muhle

12:00   Close of Conference


PARTICIPATING ORGANIZATIONS

ArQule, Inc.

Bell Laboratories/Lucent Technologies

Bohdan Automation, Inc.

Case Western Reserve University,
Department of Macromolecular Science

Chinese Academy of Sciences

Exxon Chemical Company/Univation Technologies

General Electric CR&D

Georgia Institute of Technology

Lasergenics, Inc.

Lawrence Berkeley

National Laboratory

Materials Research Group

Molecular Design Institute

Molecular Simulations, Inc.

National Institute of Standards and Technology

Pharmacopeia, Inc.

Purdue University,
Department of Chemistry

Rutgers University

SRI International

Sandia National Laboratories

Shanghai Institute of Nuclear Research,
Joint Center of Nanotechnology

Symyx Technologies

The New Jersey Center for Biomaterials and Medical Devices

Tokyo Institute of Technology,
Ceramics Materials and Structures Laboratory

Tohoku University, JAPAN,
Department of Materials Chemistry

UCLA,
Department of Chemical Engineering


Participate in Our Survey & Receive FREE Valuable Information on the State-of-the-Art in Materials Discovery

We are currently conducting a brief survey on Materials Discovery Technologies designed to identify leading methodologies, current usage, technological hurdles and an industry wish list. Survey results will provide invaluable information for competitive benchmarking and R&D trends -- and all participants who complete the survey will receive a FREE copy of the results.

There are now three convenient ways to participate:

1. You can now complete the survey online -- click here!  

2. You can also print the online survey form, complete it, and fax it to us at (617) 367-7912.

3. Or simply phone, fax or use our online form to request a copy of the survey form by mail.

You do not need to attend this event to participate in this survey.

Call For Posters

While posters on combinatorial approaches to catalyst, electronic/solid state, and polymeric discovery are especially emphasized, posters focused on other statistical and experimental design methods for materials discovery are encouraged for comparative study. Related topic areas include library design/evaluation, assay development, robotic and automated tools, lead optimization methods, chemometric techniques, mathematical models.

Commercial and academic scientists are encouraged to submit poster titles and author names as early as possible. One-page abstracts (8 1/2 x 11" with 1-inch margins), must be submitted no later than December 21, 1998 for inclusion in conference documentation. Additional poster submissions will be accepted until January 11, 1999, but may not be included in conference documentation. Please send for registration form.

Registration Information

Registration fee includes lunch on the first day, reception, refreshments and all documentation made available to us by speakers. Commercial registration is US$1295. An academic rate of US$895 is extended to all participants registering as full time employees of government and universities. Must not be affiliated with any private organizations either as consultants or owners or part owners of businesses.

Payment: All payments must be made in U.S. funds drawn on a U.S. bank. Please make check(s) payable to The Knowledge Foundation, Inc. and attach to the registration form even if you have registered by phone, fax or e-mail. Payment is required prior to the conference to confirm your registration. Confirmation of your booking will follow.

Discount Accommodations and Travel: A block of rooms has been allocated at a special reduced rate. Please make your reservations directly by December 15, 1998. When making reservations, please refer to the The Knowledge Foundation. Contact The Knowledge Foundation if you require assistance.

Venue:
The Fairmont Hotel
170 South Market Street
San Jose, CA 95113
Tel: (800) 527-4727
Fax: (408) 287-1648
www.fairmontsj.com

The Knowledge Foundation's official travel agent, Aries Travel can assist you in making all your air travel arrangements. For more information contact Aries Travel at 617-720-1420.

Substitutions/Cancellations: A substitute member of your company may replace your attendance at any time at no charge if you find your schedule prevents you from attending. Please notify us immediately so that materials can be prepared. If you do not wish to substitute your registration, we regret that your cancellation will be subject to a $100 processing fee. To receive a prompt refund, we must receive your cancellation in writing 15 days prior to the conference. Unfortunately cancellations cannot be accepted after that date. In the event that The Knowledge Foundation, Inc. cancels an event, The Knowledge Foundation, Inc. cannot resume responsibility for any travel-related costs.

Register me for this exciting conference!

Fax/mail me a complete conference brochure with session abstracts.

Another Exciting Workshop:
Combinatorial Chemistry: Beyond Pharmaceuticals, A Unique International Conference

Please visit the websites of these participating organizations:

Bohdan Automation, Inc.: Leading manufacturer of automated synthesis products for new compound discovery

National Institute of Standards and Technology

Other Educational Links and Resources:
Cambridge Soft Corporation:
Elemental Discoveries: Reactive Science Communication





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